TOTAL ANTIOXIDANT CAPACITY AND ANTIHYPERLIPIDEMIC ACTIVITY OF ALKALOID EXTRACT FROM AERIAL PART OF ANETHUM GRAVEOLENS L. PLANT
AbstractCompounds of pharmacological interest (alkaloids) were extracted and the results revealed that the extract consist of three alkaloid compounds (A, B & C). Compound (A) has been isolated from Anethum graveolens L. aerial parts by column chromatography using C6H6 : Ethanol (9:1) solvent as eluent. It was found that simultaneous administration of alkaloid compound A (500 mg/kg/day) and cholesterol for 4 weeks, significantly (P<0.01) prevented the rise in serum TC, TG, LDL-cholesterol, VLDL-cholesterol, atherogenic index and significantly (P<0.01) increased TAC and HDL-cholesterol as compared to cholesterol fed control rabbits. Thus, the results indicate antioxidant and hypolipidemic effect of alkaloid compound A of Anethum graveolens L. aerial parts.
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How to Cite
Al–Fartosy, A. J., Zearah, S. A., & Alwan, N. A. (2013). TOTAL ANTIOXIDANT CAPACITY AND ANTIHYPERLIPIDEMIC ACTIVITY OF ALKALOID EXTRACT FROM AERIAL PART OF ANETHUM GRAVEOLENS L. PLANT. European Scientific Journal, ESJ, 9(33). https://doi.org/10.19044/esj.2013.v9n33p%p